Brains On-Line B.V. The company is a contract research company in neurochemistry, with laboratories located in Groningen (the Netherlands) and San Francisco. The company facilitates preclinical drug development for medications aimed at disorders of the CNS, in particular neuropsychological disorders and neurodegenerative disorders. The studies the company carries out include: proof of principle, dose effectiveness, pharmacokinetic and pharmacodynamic relationships, bioavailability, and drug interactions/metabolism. The company specializes in monitoring dynamic neurochemical parameters in vivo and in freely-moving models.