MICRO-SPHERE S.A. Our company was founded in 1998 and started its activity in 2000 in Madonna del Piano (Switzerland) as Micro-Macinazione S.A. daughter company. In December 2008 our company was taken over by private investors and it was decided to build a new and independent site. In January 2010 we transferred our head quarter in our State-of-the-Art facility in Ponte Cremenaga (a small village in southern Switzerland's Malcantone district), few kilometres away from the original site. We have over 10 years experience in providing contract services with regard to the spray drying of aqueous and organic solutions, conventional APIs and protein as well as to formulation development, taste masking, enteric coating and containment for the pharmaceuticals companies. 21 empoloyees work at our company. cGMP compliance is the operating standard for MICRO-SPHERE S.A. and all production units meet the current environmental protection requirements. Our clean-rooms are operating in ISO 8 like class. To avoid powder cross-contamination of the production rooms the air-conditioning system uses 100% fresh air. Water for solutions is prepared by reverse osmosis and subsequently treated by electro-deionization. The quality of water is according to Eur. Pharmacopoeia and USP purified water specifications.