OpenEye Scientific Software OpenEye Scientific Software Inc. is a privately held company headquartered in Santa Fe, New Mexico, with offices in Cambridge, Massachusetts, Strasbourg, France and Nara, Japan. It was founded in 1997 to develop large-scale molecular modeling applications and toolkits. Primarily aimed towards drug discovery and design, areas of application include chemical informatics, structure generation, docking, shape comparison, electrostatics, crystallography and visualization.