Research Organics, Inc. We are an ISO 9001:2000 primary manufacturer and leading worldwide supplier of high purity biochemicals for use in molecular biology, diagnostics, cell culture, pharmaceuticals, biopharmaceuticals, life sciences and biotechnology. Founded in 1953, our company pioneered manufacture of zwitterionic biological buffers, and developed the HEPES buffer as an industry-standard, white, free-flowing powder that is colorless in solution. In the early 1980s, the copmany built large-scale production facilities at its Cleveland , Ohio corporate headquarters for bulk manufacture of buffers and biochemicals. Since the 1990s, the company has continuously expanded plant our listed products are intended for laboratory research use only and not to be used for any other purpose, including but not limited to; drug, food, food additive, cosmetics or clinical use in humans, unless otherwise stated on our product labels or in literature supplied to the buyer.