Appletree AG Appletree CI Group is an expert niche CRO and global regulatory affairs service provider with track-records in ophthalmology, medical devices, dermatology and pediatrics. We are locally present in 11 European countries and have about 50 permanent staff. By having an in-depth understanding of local cultures and customs, as well as experience with national regulations we are able to facilitate your clinical development and regulatory projects.   Expertise and Experience:   Clinical research: focus on ophthalmology, medical device investigations, dermatology and pediatric studies, phases I - IV, pre- and post-marketing studies Medical writing, consulting, pharmacovigilance, QA/ QC Data Management and Biostatistics Regulatory affairs on a global scale   Drug Regulatory Affairs:   Clinical trial authorizations in Europe Marketing authorization applications (MAA) Life cycle management, variations management Medicines and medical devices