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Sourcing Inquiry Logo AIBioTech


North America
United States
Service category
Formulation development and drug delivery, GLP services, …
Service category
Formulation development and drug delivery, GLP services, Pre-clinical development and testing, pre-clinical CRO
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AI BioTech Now Offers Analysis of Test Samples for the Presence of PDE-5 Inhibitors

Sildenafil, tadalafil, and vardenafil, are potent inhibitors of cGMP dependent-phosphodiesterase Type 5 (“PDE-5”), and are the active ingredients in Viagra, Cialis, and Levitra, respectively. The primary indication for these compounds is treatment of erectile dysfunction, and these prescription drugs are now standard treatment for erectile dysfunction in all settings, including diabetes.

Recreational use of the PDE-5 inhibitors is increasing, based mainly on the belief that these drugs increase libido and improve sexual performance. Even though the many possible adverse side-effects from over-use or misdirected use of these compounds is well documented, the compounds are often used in combination with other stimulants or opiates in formulations dubbed “sextasy”, “rockin and rollin”, trail mix”, “herbal viagra”, or simply “male enhancement products.”

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