- North America
- United States
- Service category
- Pre-clinical development and testing, pre-clinical CRO
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Biorepository & Services
BIO | OPTIONS provides high quality, well characterized human tissues and biological materials for molecular and genomic research, drug development and diagnostic testing. We offer fresh, frozen and formalin fixed paraffin embedded tissue specimens. BIO | OPTIONS specializes in providing fresh tumor tissue, blood and other biological fluids delivered the same day or overnight for your studies.
Through our extensive network of physicians, hospitals and clinical laboratories, we provide specimens from virtually all disease states, including solid tumors and autoimmune, cardiovascular, hematological, inflammatory bowel, and neurological diseases. We collect surgical tissue, bone marrow, cord blood, placenta, urine, pleural effusion and synovial fluid. Other biological fluids, including whole blood, serum and plasma are available for biomarker, circulating tumor cells and cancer stem cells studies.
Specimens are annotated with surgical pathology reports, clinical data and laboratory reports. Outcome data and detailed clinical information can also be obtained for a number of specimens.
The officers of BIO | OPTIONS consist of licensed physicians with extensive medical training and experience, including surgeons, pathologists, and general practice. By working directly with physicians and their support staff, our procurement protocols are designed to ensure the integrity of cellular components such as RNA, DNA, proteins, carbohydrates and lipids, along with the capture of relevant clinical data. We work with researchers to develop protocols that physicians and hospitals can actually implement to achieve your research needs.
All of our specimens are procured at facilities located in the United States in compliance with all applicable federal and state laws and regulations and ethical guidelines for use for research and commercial purposes. Collection facilities are located on the East and West coasts and Midwest.
BIO | OPTIONS' biorepository consists of both frozen and paraffin embedded human tissues representing the major diseases with a focus on the common tumors (e.g., breast, colon, kidney, lung, lymphoma, ovary, pancreas and prostate) and common diseases (e.g., diabetes, arthritis, autoimmune disease and infectious disease).
Frozen Biological Materials
Our frozen tissue inventory contains both snap frozen and OCT frozen specimens. Specimens are qualified for RNA integrity by gel electrophoresis. For many specimens, we have both the diseased tissue and a matched normal specimen. Frozen serum and/or plasma specimens and paraffin blocks matched to the frozen tissue specimens are also available for a select number of cases. BIO | OPTIONS' frozen specimens are stored in LN2 vapor phase freezers.
Formalin Fixed Biological Materials
We have well over 50,0000 formalin fixed paraffin embedded blocks representing all of the typical tumors and major inflammatory, cardiovascular, neurological, and autoimmune diseases. Normal tissue specimens are also available.
Customized RNA, DNA, cDNA and proteins can be provided from our tissue inventory or yours.
BIO | OPTIONS will also provide specimens with customized preparation and preservation methods, including surgical tumor specimens with pre and post operative blood. Detailed clinical information for your specific research needs can be obtained.
Longitudinal Outcomes Collections
Biological materials with longitudinal outcome data to determine disease progression and treatment response can be collected for your particular research needs. Our network of large medical groups, clinics, physician specialists and hospitals cover essentially all of the major medical conditions.
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