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Pre-Clinical Research Services, Inc.

North America
United States
Service category
Pre-clinical development and testing, pre-clinical CRO
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Key services




FDA-GLP Compliant & Non-GLP Experimental Surgery

  • Minimally Invasive Surgery
  • Electrosurgery
  • GLP & Non-GLP Surgery Models
  • Anesthesia Services
  • Surgeon Training Facilities


Medical Imaging Studies (OEC 9900 Digital Fluoroscopy)


Pathology & Histopathology


Pharmacological Disease Models

  • Osteoarthritis models
  • Dermal sensitization


Anemia Models


Pharmacokinetic Testing

  • Non-naïve dog colony
  • Duodenal ports
  • Dogs, pigs, rabbits, rodents


Toxicology Studies

  • Acute, subchronic, chronic
  • Dose range finding
  • Max tolerated dose studies


Osteoarthritis Models

  • Dogs and rabbits.
  • Surgically, immunologically or pharmacologically induced.
  • Intra-articular, oral or IV dosing – single, multiple, chronic.
  • Biomarkers – blood, urine, synovial fluid.
  • Orthopedic research diagnostic capabilities that include Kistler force plate data collection and gait analysis.
  • MRI scans and image analysis.
  • Gross and histopathology scoring and evaluation.

Species available


We can quickly obtain a range of purpose-bred animals for your study needs. As a USDA-licensed facility, we’re proud of maintaining the highest level of humane care and treatment for:

  • Dogs – Including a non-naïve resident colony
  • Pigs – Domestic, Yucatan & Gottingen Minipigs
  • Rats, mice, hamsters, guinea pigs
  • Rabbits
  • Cats
  • Sheep


Facilities and Equipment


Located about 75 minutes from Denver International Airport alongside the magnificent Rocky Mountains, our advanced, 22,000-square-foot facility houses such sophisticated equipment as:

  • OEC 9900 Digital Fluoroscopy for angiography, minimally invasive needle or electrode placement, contrast studies such as barium GI series or spine studies, or digital images for surgical device implants.
  • Extensive surgery suites allow up to seven surgeries at once.
  • Latest veterinary anesthesia and intra-operative physiologic monitoring.
  • Endoscopy and arthroscopic surgical equipment.
  • Cutting-edge electrosurgery equipment, including vessel sealing.
  • Orthopedic research diagnostic capabilities, include force plate testing and gait analysis.
  • Surgeon training labs with lecture and operating rooms.



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