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CRO for mouse MPTP model

  • Pre-clinical development and testing, pre-clinical CRO
  • Biopharmaceuticals
  • Europe
  • 08/03/2012

Description

We are looking for a CRO to study neuroprotective properties of investigational compound(s) in a mouse MPTP model. The study set-up should contain:

- four treatment groups including one positive reference compound (obligatory) selected by service provider, and relevant control groups
- acute-to-subchronic (max. 10 days) treatment period
- relevant outcome measures showing the integrity of nigrostriatal dopaminergic pathway in which behavioural assessment can be secondary outcome measure but is not acceptable as the sole primary outcome measure

Requirements

  • Reference data mandatory

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