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Looking for provider for testing 2 compounds for their efficacy on bleomycin-induced lung fibrosis

  • Pre-clinical development and testing, pre-clinical CRO
  • Human Medicines, Biopharmaceuticals, Animal Medicines
  • Worldwide
  • 09/30/2014

Description

We are looking at 2 tests and 1 vehicle

What is your positive control, what would you use?

Dozing frequency BID

N=10 per group

Could you also give me an estimate for BALF and cytokines, tgf-Beta

I.E. I would like to add…

Endpoints: measure effects on pro-inflamm cytokines (IL1b, IL6, TGFb) and MMPs. We also need BALF flow cytometry data to look at infiltrating fibrocytes and collagen-positive cells.

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