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Seeking CRO able to do in vitro studies with human monocytes/macrophages, examination of drug uptake and cytokine release

  • GLP services, Clinical development and testing, clinical CRO
  • Human Medicines
  • Europe
  • 05/10/2012


Looking for a CRO to measure the uptake of drug candidates by human monocytes/macrophages (or Kupffer cells if available). FACS would be the best method, the potential to examine cells with confocal fluorescence microscopy would be an advantage. We can provide the candidates in fluorescently labelled form. In addition we would like to assess cytokine release from the phagocytic cells with and without extra stimuli such as LPS.

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